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KMID : 0869620230400040409
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Journal of Korean Society of Hospital Pharmacists
2023 Volume.40 No. 4 p.409 ~ p.422
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Prevalence of Drug-related Admissions and Associated Factors among Geriatric Center Patients
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Kim Seo-Young
Kim Da-Hye
Park So-Yeon
Kim Yoon-Hee
Namgung Hyung-Wook
Lee Jung-Hwa
Lee Euni
Choi Jung-Yeon
Lee Ju-Yeun
Kim Kwang-Il
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Abstract
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Background : Older adults are at a higher risk of drug-related admissions (DRA) compared with younger adults. This study aimed to evaluate the prevalence of DRA and identify the associated factors among the geriatric center elderly patients.
Methods : This retrospective cross-sectional study included older patients admitted at the geriatric center at Seoul National University Bundang Hospital from August 1, 2020 to June 30, 2022. Two pharmacists independently assessed DRA cases following the DRA adjudication guide and assessed their causality and preventability using the Schumock and Thornton criteria. We analyzed the type of DRA, medications involved, preventive measures, and the associated factors.
Results : Among the 403 patients included in the study, 26.3% (106 patients) experienced 125 drug-related problems causing admission, of which 55.2% were preventable. The most common DRAs were gastrointestinal hemorrhage (21 cases, 16.8%), followed by acute kidney injury (16 cases, 12.8%). A total of 179 medications were implicated in these cases, with the most prevalent classes being anticoagulants (23 cases, 12.8%) and nonsteroidal anti-inflammatory drugs (21 cases, 11.7%). Factors associated with DRAs included poor adherence (aOR=3.69, 95% CI 1.40-9.73), use of 10 or more drugs (aOR=2.12, 95% CI 1.30-3.45), and a higher number of potentially inappropriate medications for the elderly (aOR=1.60, 95% CI 1.10-2.33).
Conclusion : Approximately one-fourth of admissions to the geriatric center were related to drug-related problems. Alarmingly, over half of these incidents were preventable, highlighting a critical need for improved medication management strategies among elderly patients.
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KEYWORD
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Drug-related Admission, Elderly, Potentially inappropriate medications, Adherence
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